Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21445083 | 0.78 | MAOB (0.58) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL6243624 | 0.76 | KDM4E (0.80) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL5672293 | 0.75 | HPGD (0.50) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL1368561 | 0.74 | MAOB (0.68) | MAOBKDM4EALDH1A1TSHRMAOA | |
| SCHEMBL8304474 | 0.74 | MAOB (0.59) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| 3-Hydroxycoumarin SCHEMBL27837419 | 0.74 | HPGD (0.67) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL11321171 | 0.73 | MAOB (1.00) | MAOBKDM4EALDH1A1HSD17B10MAOA | |
| 3-Hydroxycoumarin SCHEMBL11497836 | 0.73 | HPGD (0.65) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL11639714 | 0.73 | HPGD (0.55) | MAOBKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL28124979 | 0.72 | HPGD (0.58) | MAOBKDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |