Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137226 | 0.87 | EDNRB (0.39) | TDP1POLBCTDSP1EDNRBEDNRA | |
| SCHEMBL9994809 | 0.84 | EDNRB (0.38) | TDP1EDNRBEDNRAGRM2GRM3 | |
| SCHEMBL1436171 | 0.84 | EDNRB (0.38) | TDP1EDNRBEDNRAGRM2GRM3 | |
| SCHEMBL8918724 | 0.82 | KDM4E (0.39) | TDP1POLBCTDSP1EDNRBEDNRA | |
| SCHEMBL31509894 | 0.82 | KDM4E (0.39) | TDP1POLBCTDSP1EDNRBEDNRA | |
| SCHEMBL15247103 | 0.71 | KDM4E (0.42) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL2699713 | 0.71 | KDM4E (0.42) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL12834033 | 0.69 | KDM4E (0.30) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL24489924 | 0.69 | KDM4E (0.36) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL9306839 | 0.68 | PPP5C (0.36) | TDP1POLBGRM2GRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366302-A | HEAT RESISTANCE CURING AGENTS | LORD CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |