⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535097 | 0.72 | — | — | |
| SCHEMBL10947039 | 0.67 | — | — | |
| SCHEMBL9837843 | 0.65 | — | — | |
| SCHEMBL61233 | 0.62 | — | — | |
| SCHEMBL4217446 | 0.62 | — | — | |
| SCHEMBL1950819 | 0.62 | — | — | |
| SCHEMBL6090956 | 0.62 | — | — | |
| SCHEMBL9178861 | 0.60 | — | — | |
| SCHEMBL720480 | 0.60 | — | — | |
| SCHEMBL1006909 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342769-A | 2-[(Methylsulfinyl)acetyl]-3-heterocyclicindoles and derivatives thereof as immunosuppressants | SCHERING CORPORATION (US) | 1982-08-03 | — | — | US | claimed |
| US-4328345-A | Pyridyl substituted indoles | SCHERING CORPORATION (US) | 1982-05-04 | — | — | US | claimed |
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| CN-1003712-B | Process for preparing 6- (1-acyl-1-hydroxymethyl or acetoxymethyl) penicillanic acid derivatives | 美国辉瑞有限公司 | 1989-03-29 | — | — | CN | disclosed |
| US-4342769-A | 2-[(Methylsulfinyl)acetyl]-3-heterocyclicindoles and derivatives thereof as immunosuppressants | SCHERING CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| US-4328345-A | Pyridyl substituted indoles | SCHERING CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0010617-B1 | NOVEL 2-SUBSTITUTED-3-HETEROCYCLYLINDOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4225711-A | Substituted 2-[(methylsulfinyl)acetyl]-3-heterocyclicindoles and their use as immunosuppressants | SCHERING CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |
| EP-0010617-A1 | Novel 2-substituted-3-heterocyclylindoles, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-05-14 | — | — | EP | disclosed |
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |