Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1125958 | 0.92 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL1126031 | 0.91 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL1125890 | 0.88 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL1126026 | 0.84 | NR1H2 (0.67) | NR1H2NR1H3 | |
| SCHEMBL1126028 | 0.84 | NR1H2 (0.67) | NR1H2NR1H3 | |
| SCHEMBL1126253 | 0.84 | NR1H2 (0.61) | NR1H2NR1H3 | |
| SCHEMBL1126257 | 0.84 | NR1H2 (0.61) | NR1H2NR1H3 | |
| SCHEMBL3854059 | 0.82 | NR1H2 (0.77) | NR1H2NR1H3 | |
| SCHEMBL1125104 | 0.81 | NR1H2 (0.68) | NR1H2NR1H3 | |
| SCHEMBL3859944 | 0.81 | NR1H2 (0.75) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284157-A1 | Quinolines useful in treating cardiovascular disease | Wyeth (US) | 2011-02-16 | — | — | EP | claimed |
| JP-2007516258-A | — | — | 2007-06-21 | — | — | JP | claimed |
| EP-1692111-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | Wyeth, A Corporation of the State of Delaware (US) | 2006-08-23 | — | — | EP | claimed |
| WO-2005058834-A2 | QUINOLINES USEFUL IN TREATING CARDIOVASCULAR DISEASE | WYETH (US) | 2005-06-30 | — | — | WO | claimed |