Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263159 | 1.00 | PTGS1 (0.54) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11259271 | 0.94 | PTGS1 (0.46) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11259279 | 0.94 | PTGS1 (0.46) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11273492 | 0.91 | PTGS1 (0.57) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11273489 | 0.91 | PTGS1 (0.57) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11271705 | 0.85 | TDP1 (0.57) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11271716 | 0.85 | TDP1 (0.57) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11268169 | 0.84 | PTGS1 (0.48) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11268184 | 0.84 | PTGS1 (0.48) | PTGS1MAPTNR1I2SLC22A6SLC22A8 | |
| SCHEMBL11259505 | 0.81 | NR1I2 (0.73) | PTGS1MAPTNR1I2SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |