Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 7/20 | 0.66 |
| ▸ | DKK1 | O94907 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.59 |
| ▸ | CA9 | Q16790 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA6 | P23280 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CDK4 | P11802 | 2/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004300 | 0.83 | CA1 (0.69) | CA1CA2CA9CA12CA14 | |
| SCHEMBL4661788 | 0.82 | IKBKB (0.67) | IKBKBDKK1GSK3BMAPK8MAPK10 | |
| SCHEMBL3518049 | 0.81 | IKBKB (0.79) | IKBKBDKK1GSK3BMAPK8MAPK10 | |
| SCHEMBL1652316 | 0.80 | IKBKB (0.64) | IKBKBDKK1GSK3BCA1CA2 | |
| SCHEMBL19575358 | 0.79 | AURKA (0.57) | IKBKBCDK2CDK4AURKACDK1 | |
| SCHEMBL3520305 | 0.79 | IKBKB (0.70) | IKBKBDKK1GSK3BMAPK8MAPK10 | |
| SCHEMBL23887628 | 0.79 | AURKA (0.56) | IKBKBDKK1GSK3BMAPK8MAPK10 | |
| SCHEMBL30086808 | 0.79 | AURKA (0.56) | IKBKBDKK1GSK3BMAPK8MAPK10 | |
| SCHEMBL10225814 | 0.79 | SCN9A (0.58) | IKBKBCDK2AURKACDK1CCNB1 | |
| SCHEMBL14264262 | 0.78 | CA1 (0.86) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336270-A | BACTERICIDES, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1982-06-22 | — | — | US | disclosed |
| US-4160833-A | ANIMAL FEED ADDITIVE AND MICROBIOCIDE | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-3991124-A | FOR CONTROLLING MICROORGANISMS AND HELMINTHS | CIBA-GEIGY CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3985745-A | ACTIVE AGAINST MICROORGANISMS | CIBA-GEIGY CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3956402-A | MICROBIOCIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |