Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267573 | 1.00 | EPHX2 (0.39) | EPHX2ALOX15KMT2ATRPV1DRD2 | |
| SCHEMBL11271812 | 0.85 | TRPV1 (0.36) | EPHX2KMT2ATRPV1ALDH1A1 | |
| SCHEMBL11271808 | 0.85 | TRPV1 (0.36) | EPHX2KMT2ATRPV1ALDH1A1 | |
| SCHEMBL11260254 | 0.85 | SMYD3 (0.36) | EPHX2KMT2ATRPV1 | |
| SCHEMBL11260258 | 0.85 | SMYD3 (0.36) | EPHX2KMT2ATRPV1 | |
| Hydrochloric Acid SCHEMBL11274019 | 0.84 | SMYD3 (0.35) | EPHX2KMT2ATRPV1 | |
| SCHEMBL11263328 | 0.84 | EPHX2 (0.36) | EPHX2KMT2ATRPV1 | |
| SCHEMBL11263325 | 0.84 | EPHX2 (0.36) | EPHX2KMT2ATRPV1 | |
| Hydrochloric Acid SCHEMBL11274027 | 0.84 | SMYD3 (0.35) | EPHX2KMT2ATRPV1 | |
| Hydrochloric Acid SCHEMBL11264132 | 0.83 | XIAP (0.40) | EPHX2KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315006-A | Benzoxocin derivatives having anxiolytic and anti-convulsant activities | GLAXO GROUP LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |
| EP-0024843-A1 | 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-03-11 | — | — | EP | disclosed |