Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | PTPRB | P23467 | 3/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075964 | 0.91 | PDE5A (0.36) | SMN1; SMN2PDE5AMAPTTSHRMAPK1 | |
| SCHEMBL9076896 | 0.90 | ABCB1 (0.41) | PI4KBCCR2PTPRBABCB1SMN1; SMN2 | |
| SCHEMBL11204633 | 0.88 | PI4KB (0.42) | PI4KBCCR2PTPRBCTSSCTSK | |
| SCHEMBL22017475 | 0.88 | PI4KB (0.42) | PI4KBCCR2PTPRBCTSSCTSK | |
| SCHEMBL10425304 | 0.84 | PDE5A (0.37) | SMN1; SMN2PDE5AMAPTTSHRMAPK1 | |
| SCHEMBL9075472 | 0.84 | HDAC3 (0.38) | PI4KBPTPRBABCB1SMN1; SMN2CTSS | |
| SCHEMBL20571757 | 0.83 | MAPK1 (0.48) | CCR2PTPRBSMN1; SMN2CTSSMAPT | |
| SCHEMBL9073597 | 0.81 | MAPT (0.43) | SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL9075797 | 0.81 | PDE5A (0.37) | SMN1; SMN2PDE5AMAPTTSHRMAPK1 | |
| SCHEMBL23452689 | 0.81 | PTPRB (0.39) | PI4KBPTPRBABCB1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |