Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251043 | 0.88 | APP (0.56) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11249955 | 0.85 | PIK3CD (0.61) | APPCYP1A2CYP3A4HSD17B10KDM4E | |
| SCHEMBL11253996 | 0.82 | PIK3CD (0.57) | APPMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL11255864 | 0.81 | APP (0.56) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11264896 | 0.81 | APP (0.59) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11252575 | 0.80 | APP (0.55) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11250201 | 0.79 | APP (0.63) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11251275 | 0.79 | GBA1 (0.63) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL11245481 | 0.78 | APP (0.53) | APPMEN1KMT2APDE5ACYP1A2 | |
| SCHEMBL8897898 | 0.78 | CYP1A2 (0.68) | APPMEN1KMT2APDE5ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |