Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 13/20 | 0.46 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377837 | 0.90 | KDM4E (0.56) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL11270225 | 0.88 | TSHR (0.54) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL1403482 | 0.86 | KDM4E (0.50) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL11377328 | 0.83 | MAPK1 (0.53) | KDM4EL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10931678 | 0.82 | P4HTM (0.44) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL28022486 | 0.79 | P4HTM (0.44) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL4331572 | 0.77 | P4HTM (0.53) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL2743888 | 0.75 | P4HTM (0.53) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL11280277 | 0.75 | P4HTM (0.45) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A | |
| SCHEMBL11671608 | 0.74 | MAPK1 (0.50) | KDM4EL3MBTL1ALDH1A1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066242-A1 | Tocopheryl ester of 5-substituted picolinic acid, process for its production, and pharmaceutical composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-12-08 | — | — | EP | claimed |
| US-4260620-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4197302-A | HYPOTENSIVE AGENTS, 5-ETHERIFIED, ALSO ESTERS, AMIDES, HYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |