Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254486 | 0.94 | MAPK1 (0.46) | ALDH1A1CYP3A4FAAHMAPK1RAB9A | |
| SCHEMBL11433969 | 0.92 | GAA (0.44) | ALDH1A1FAAHMAPK1RAB9ANPC1 | |
| SCHEMBL11247577 | 0.86 | MAPK1 (0.45) | ALDH1A1CYP3A4FAAHMAPK1NPC1 | |
| SCHEMBL11267015 | 0.86 | GAA (0.45) | ALDH1A1CYP3A4FAAHMAPK1RAB9A | |
| SCHEMBL11261735 | 0.85 | GAA (0.42) | ALDH1A1CYP3A4FAAHMAPK1RAB9A | |
| SCHEMBL11667292 | 0.85 | MAPK1 (0.44) | ALDH1A1CYP3A4FAAHMAPK1NPC1 | |
| SCHEMBL11254034 | 0.85 | MAPK1 (0.49) | ALDH1A1CYP3A4FAAHMAPK1NPC1 | |
| SCHEMBL11426647 | 0.85 | GAA (0.45) | ALDH1A1CYP3A4FAAHMAPK1RAB9A | |
| SCHEMBL11431875 | 0.82 | GAA (0.47) | ALDH1A1CYP3A4FAAHMAPK1RAB9A | |
| SCHEMBL11437201 | 0.80 | GAA (0.43) | ALDH1A1CYP3A4FAAHMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317674-A | Diurethanes, process for making the same and selective herbicide composition containing same | SCHERING AG (DE) | 1982-03-02 | — | — | US | claimed |