Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926687 | 0.90 | SLC6A2 (0.42) | NAAASLC6A2SLC6A4SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL13268822 | 0.82 | PTGDR2 (0.41) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL674077 | 0.80 | PTGDR2 (0.42) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3745489 | 0.80 | PTGDR2 (0.42) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3756190 | 0.80 | SLC6A2 (0.39) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL677543 | 0.80 | PTGDR2 (0.42) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11754963 | 0.80 | PTGDR2 (0.42) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL477417 | 0.80 | PTGDR2 (0.46) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5283227 | 0.80 | PTGDR2 (0.42) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5821254 | 0.80 | PTGDR2 (0.46) | PTGDR2NAAASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |