Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277514 | 0.81 | HTT (0.60) | HPGDSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL21540140 | 0.81 | KMT2A (0.59) | HPGDSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL21594744 | 0.81 | KMT2A (0.59) | HPGDSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL11278425 | 0.80 | HTT (0.59) | HPGDSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL11286791 | 0.80 | HTT (0.59) | HPGDSMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL8828176 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1KMT2A | |
| SCHEMBL13280179 | 0.74 | HPGD (0.74) | HPGDSMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL26125381 | 0.74 | HPGD (0.74) | HPGDSMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL17664707 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1KMT2ATP53 | |
| SCHEMBL26128333 | 0.74 | HPGD (0.62) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |