Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990012 | 0.88 | TSHR (0.48) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1990014 | 0.88 | TSHR (0.48) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1126564 | 0.88 | TSHR (0.58) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1126773 | 0.83 | TSHR (0.49) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16500353 | 0.82 | TSHR (0.53) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1127521 | 0.81 | TSHR (0.52) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1127122 | 0.81 | MAPT (0.53) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1126610 | 0.81 | TSHR (0.47) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1126609 | 0.81 | TSHR (0.47) | TSHRARMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1127192 | 0.80 | TSHR (0.51) | TSHRARMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |