Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250611 | 0.87 | DYRK1A (0.47) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9963507 | 0.87 | NPC1 (0.45) | PIK3CGKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11340877 | 0.86 | DYRK1A (0.48) | KMT2ALRRK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL383066 | 0.84 | NPC1 (0.59) | KMT2ASCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11105682 | 0.84 | NPC1 (0.59) | KMT2ASCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL383067 | 0.84 | NPC1 (0.59) | KMT2ASCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11100379 | 0.83 | ACP1 (0.50) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11108686 | 0.82 | DYRK1A (0.42) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11106758 | 0.81 | DYRK1A (0.62) | KMT2ASCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11100178 | 0.80 | PPARA (0.57) | SMN1; SMN2HDAC6SENP7DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |