Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12678366 | 0.88 | FGFR3 (0.70) | FGFR3 | |
| SCHEMBL1126412 | 0.88 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL1126562 | 0.83 | FGFR3 (0.77) | FGFR3 | |
| SCHEMBL1126224 | 0.83 | FGFR3 (0.74) | FGFR3 | |
| SCHEMBL3315565 | 0.82 | FGFR3 (0.51) | FGFR3 | |
| SCHEMBL3313560 | 0.82 | FGFR3 (0.51) | FGFR3 | |
| SCHEMBL1126739 | 0.82 | FGFR3 (0.82) | FGFR3 | |
| SCHEMBL1126344 | 0.81 | FGFR3 (0.61) | FGFR3 | |
| SCHEMBL12678386 | 0.80 | FGFR3 (0.85) | FGFR3 | |
| SCHEMBL1126071 | 0.80 | FGFR3 (0.71) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2011-02-16 | — | — | EP | claimed |