Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 5/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275840 | 0.90 | ALPG (0.61) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11263778 | 0.88 | ALPG (0.58) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11269862 | 0.83 | ALPG (0.64) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11276137 | 0.83 | ALPG (0.67) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11261079 | 0.81 | ALPG (0.61) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11005250 | 0.80 | ALPG (0.60) | ALPGAKR1B1PTAFRTBXAS1 | |
| SCHEMBL11276470 | 0.80 | ALPG (0.63) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11275156 | 0.80 | ALPG (0.60) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11009173 | 0.78 | ALPG (0.71) | ALPGAKR1B1ALDH1A1KDM4EHPGD | |
| SCHEMBL11270447 | 0.77 | ALPG (0.77) | ALPGAKR1B1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |