SCHEMBL11265989

SCHEMBL11265989

CCCCCCCCCCc1ncncn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.42
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGS2 P35354 4/20 0.38
ALDH1A1 P00352 3/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TBXAS1 P24557 2/20 0.38
CYP3A4 P08684 2/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
HSPD1 P10809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27794520 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL20499801 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL20747030 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL28091635 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL2708603 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL28254738 1.00 KCNH2 (0.42) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
Fluoride SCHEMBL28274021 0.98 KCNH2 (0.41) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL27872105 0.98 KCNH2 (0.41) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
SCHEMBL306173 0.98 TDP1 (0.39) KCNH2TDP1L3MBTL1PTGS2ALDH1A1
Cyanide SCHEMBL27430349 0.93 TDP1 (0.37) KCNH2TDP1L3MBTL1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019153674-A1 IGG EPITOPE AND APPLICATION THEREOF AS TARGET 北京大学 2019-08-15 WO disclosed
US-4354968-A Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component BAYER AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed