Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | KAT6A | Q92794 | 11/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | FLT1 | P17948 | 2/20 | 0.55 |
| ▸ | FLT4 | P35916 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366923 | 0.83 | HPGD (0.71) | HPGDPOLBKAT6AKDM4EFLT1 | |
| SCHEMBL20232823 | 0.83 | KAT6A (1.00) | HPGDKAT6A | |
| SCHEMBL10765828 | 0.82 | KDM4E (0.72) | HPGDPOLBKDM4EFLT1FLT4 | |
| SCHEMBL4196234 | 0.79 | KDM4E (0.68) | HPGDPOLBKDM4EFLT1FLT4 | |
| SCHEMBL653805 | 0.79 | FLT1 (0.77) | HPGDPOLBKAT6AKDM4EFLT1 | |
| SCHEMBL11442730 | 0.79 | FLT1 (0.82) | HPGDPOLBKAT6AKDM4EFLT1 | |
| SCHEMBL10633856 | 0.79 | HPGD (0.65) | HPGDPOLBKAT6AKDM4EFLT1 | |
| SCHEMBL365236 | 0.79 | HPGD (0.65) | HPGDPOLBKAT6AGAA | |
| SCHEMBL28018539 | 0.79 | HPGD (0.65) | HPGDPOLBKAT6AGAA | |
| SCHEMBL8855736 | 0.78 | KDM4E (0.66) | HPGDPOLBKDM4EFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100374416-C | P-(sulfonyl)-aryl and heteroaryls amines | HOFFMANN LA ROCHE CO LTD (CH) | 2008-03-12 | — | — | CN | disclosed |
| CN-1708478-A | P-(sulfonyl)-aryl and heteroaryls amines | HOFFMANN LA ROCHE (CH) | 2005-12-14 | — | — | CN | disclosed |
| US-4347380-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4266078-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-05-05 | — | — | US | disclosed |