Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11249801 | 0.97 | TSHR (0.67) | TSHRDGKAALDH1A1THRBFNTA | |
| Methacrylic Acid SCHEMBL15284903 | 0.97 | TSHR (0.67) | TSHRDGKAALDH1A1THRBFNTA | |
| Methacrylic Acid SCHEMBL27706309 | 0.93 | TSHR (0.56) | TSHRDGKAALDH1A1THRBTDP1 | |
| SCHEMBL3503189 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL11157175 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL3503326 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL1093181 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL1093904 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL9441806 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 | |
| SCHEMBL27646438 | 0.92 | TSHR (0.61) | TSHRDGKAALDH1A1TDP1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311841-A | REACTION WITH ALDEHYDE, CONDENSATION | PETROLITE CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |