Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL11249803 | 0.97 | TSHR (0.61) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL28214986 | 0.91 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL27932227 | 0.91 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL28107306 | 0.91 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL28107647 | 0.91 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL27934279 | 0.91 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH | |
| Methacrylic Acid SCHEMBL11252016 | 0.90 | TSHR (0.63) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL11146407 | 0.89 | TSHR (0.55) | TSHREP300HCAR2NAAAFAAH | |
| Acrylic Acid SCHEMBL11544601 | 0.88 | TSHR (0.53) | TSHREP300HCAR2NAAAFAAH | |
| SCHEMBL8752883 | 0.88 | TSHR (0.58) | TSHREP300HCAR2NAAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311841-A | REACTION WITH ALDEHYDE, CONDENSATION | PETROLITE CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |