Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 15/20 | 0.62 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11394217 | 0.98 | HCAR2 (0.61) | HCAR2HCAR3DAO | |
| SCHEMBL11394211 | 0.84 | HCAR2 (0.43) | HCAR2HCAR3DAO | |
| SCHEMBL11435557 | 0.84 | HCAR2 (0.43) | HCAR2HCAR3DAO | |
| SCHEMBL12703805 | 0.81 | HCAR2 (0.64) | HCAR2HCAR3DAO | |
| SCHEMBL11435544 | 0.78 | KMT2A (0.47) | HCAR2HCAR3 | |
| SCHEMBL5599320 | 0.77 | HCAR2 (1.00) | HCAR2HCAR3DAO | |
| SCHEMBL3954952 | 0.76 | HCAR2 (1.00) | HCAR2HCAR3DAO | |
| SCHEMBL7372956 | 0.76 | HCAR2 (0.69) | HCAR2HCAR3DAO | |
| SCHEMBL9014909 | 0.76 | HCAR2 (0.69) | HCAR2HCAR3DAO | |
| SCHEMBL15056191 | 0.75 | HCAR2 (0.37) | HCAR2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323576-A | TREATMENT OF HYPERLIPEMIA | MORISHITA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | claimed |
| JP-56073024-A | — | — | None | — | — | JP | disclosed |
| US-4323576-A | TREATMENT OF HYPERLIPEMIA | MORISHITA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| JP-S5673024-A | ANTIHYPERLIPEMIC AGENT | MORISHITA SEIYAKU KK | 1981-06-17 | — | — | JP | disclosed |
| EP-0029364-A1 | 5-Alkylpyrazol-3-carboxylic acid derivatives for use in therapy | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |
| EP-0029364-A1 | 5-Alkylpyrazol-3-carboxylic acid derivatives for use in therapy | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |
| EP-0029363-A1 | Pyrazole derivatives, process for their preparation and pharmaceutical compositions containing them | MORISHITA PHARMACEUTICAL CO. LTD. (JP) | 1981-05-27 | — | — | EP | disclosed |