Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11267245 | 1.00 | — | — | |
| SCHEMBL6566430 | 0.96 | — | — | |
| Bromide SCHEMBL2858814 | 0.74 | — | — | |
| Bromide SCHEMBL7203624 | 0.73 | — | — | |
| Bromide SCHEMBL9022666 | 0.70 | — | — | |
| Bromide SCHEMBL7722693 | 0.70 | — | — | |
| SCHEMBL16706957 | 0.69 | — | — | |
| SCHEMBL15904592 | 0.69 | — | — | |
| SCHEMBL31753913 | 0.69 | — | — | |
| SCHEMBL25094981 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |