Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.96 |
| ▸ | POLB | P06746 | 3/20 | 0.96 |
| ▸ | MEN1 | O00255 | 3/20 | 0.96 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.60 |
| ▸ | MYC | P01106 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CD69 | Q07108 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268162 | 1.00 | NPC1 (0.96) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL156331 | 0.98 | NPC1 (1.00) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL93488 | 0.98 | NPC1 (1.00) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL18821707 | 0.98 | NPC1 (1.00) | NPC1KMT2APOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL2050403 | 0.96 | NPC1 (0.96) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL29260799 | 0.93 | NPC1 (0.90) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL5306452 | 0.88 | NPC1 (0.74) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL33368 | 0.86 | NPC1 (0.77) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL30329638 | 0.86 | NPC1 (0.77) | NPC1KMT2APOLBMEN1RAB9A | |
| SCHEMBL7157735 | 0.86 | NPC1 (0.77) | NPC1KMT2APOLBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | disclosed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | disclosed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | disclosed |
| US-3973962-A | Aggregate photoconductive composition containing combination of pyrylium dye salts | EASTMAN KODAK COMPANY (US) | 1976-08-10 | — | — | US | disclosed |