Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272520 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL11258326 | 0.87 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1KMT2A | |
| SCHEMBL11270651 | 0.86 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL11260166 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL11264966 | 0.85 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL11271468 | 0.84 | CYP11B1 (0.43) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL11271165 | 0.84 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1KMT2A | |
| SCHEMBL11268909 | 0.82 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1KMT2AMEN1 | |
| SCHEMBL11262618 | 0.82 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP19A1KMT2A | |
| SCHEMBL11257492 | 0.82 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |