Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268765 | 0.91 | GAA (0.42) | GAAKMT2AALDH1A1NPSR1MAPT | |
| SCHEMBL11258761 | 0.85 | GAA (0.61) | GAAKMT2AATMALDH1A1HPGD | |
| SCHEMBL11258922 | 0.83 | GAA (0.59) | GAAKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11416741 | 0.82 | GAA (0.58) | GAAKMT2AATMALDH1A1MEN1 | |
| SCHEMBL11410655 | 0.82 | GAA (0.58) | GAAKMT2AATMALDH1A1MAPT | |
| SCHEMBL10421881 | 0.82 | GAA (0.58) | GAAALDH1A1MAPTHTTCNR2 | |
| SCHEMBL11257459 | 0.81 | GAA (0.57) | GAAKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11625579 | 0.80 | GAA (0.73) | GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11806876 | 0.80 | GAA (0.55) | GAAALDH1A1NPSR1HPGDSMN1; SMN2 | |
| SCHEMBL11806459 | 0.79 | GAA (0.54) | GAAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345932-A | BENZOFURANYL ESTERS | FISONS LIMITED (GB) | 1982-08-24 | — | — | US | disclosed |
| US-4157255-A | 2-AMINO-BENZOFURAN-2-YL METHANE SULFONATE | FISONS LIMITED (GB) | 1979-06-05 | — | — | US | disclosed |
| US-4120871-A | HERBICIDES, PLANT GROWTH REGULATORS | FISONS LIMITED (GB) | 1978-10-17 | — | — | US | disclosed |