Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740901 | 0.89 | KMT2A (0.56) | KMT2AMEN1NPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL21645347 | 0.87 | KMT2A (0.54) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL16470335 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL1102071 | 0.83 | KMT2A (0.71) | KMT2AMEN1NPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL15527542 | 0.83 | KMT2A (0.66) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL11582992 | 0.82 | POLB (0.63) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL1740370 | 0.81 | KMT2A (0.63) | KMT2AMEN1NPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL27491393 | 0.81 | KMT2A (0.69) | KMT2AMEN1NPC1POLBRAB9A | |
| SCHEMBL11137991 | 0.81 | MEN1 (0.69) | KMT2AMEN1NPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL7258086 | 0.80 | KMT2A (0.61) | KMT2AMEN1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4115564-A | Treatment of diarrhea with amidinoureas | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |