Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763792 | 0.94 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL29207956 | 0.92 | TLR8 (0.49) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL11577551 | 0.89 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL28275474 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL30254408 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL5713368 | 0.86 | TLR8 (0.51) | KDM4EALDH1A1HPGDHSD17B10TLR8 | |
| SCHEMBL4887109 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL29611102 | 0.86 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10RAB9A | |
| SCHEMBL11148331 | 0.84 | TLR8 (0.53) | KDM4EALDH1A1HPGDHSD17B10TLR8 | |
| SCHEMBL14888795 | 0.84 | TLR8 (0.53) | KDM4EALDH1A1HPGDHSD17B10TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346015-A | Method of improving antiwear properties of high temperature hydrocarbon compositions | UNION CARBIDE CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| US-4097393-A | ENDCAPPED POLYDIMETHYLSILOXANE, BRAKE FLUIDS | UNION CARBIDE CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |