Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100426 | 0.80 | KMT2A (0.59) | KMT2AMEN1HSD17B10MAPTALDH1A1 | |
| SCHEMBL624764 | 0.78 | CYP2C9 (0.58) | RAB9ANPC1MAPTALDH1A1CYP2C19 | |
| SCHEMBL5641851 | 0.78 | SMN1; SMN2 (0.59) | KMT2AMEN1MAPTALDH1A1CYP3A4 | |
| SCHEMBL6939496 | 0.78 | MEN1 (0.63) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL2205749 | 0.77 | HSD17B10 (0.62) | KMT2ARAB9AHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL23675419 | 0.77 | NPC1 (0.65) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL2012871 | 0.77 | HSD17B10 (0.49) | KMT2AMEN1RAB9ANPC1HSD17B10 | |
| SCHEMBL2528975 | 0.76 | MAPT (0.49) | KMT2AMEN1RAB9AHSD17B10MAPT | |
| SCHEMBL844111 | 0.76 | HSD17B10 (0.60) | KMT2AHSD17B10MAPTALDH1A1CYP1A2 | |
| SCHEMBL2084055 | 0.76 | HSD17B10 (0.60) | KMT2AHSD17B10ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003619-B1 | HETEROCYCLIC-SUBSTITUTED ANILIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND A METHOD OF CONTROLLING UNDESIRED PLANT GROWTH USING THEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-05-05 | — | — | EP | disclosed |
| EP-0003619-A2 | Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-22 | — | — | EP | disclosed |