Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284437 | 0.94 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1CYP19A1POLB | |
| SCHEMBL11287184 | 0.91 | CYP11B1 (0.44) | CYP11B1CYP11B2CYP19A1POLB | |
| SCHEMBL11274846 | 0.90 | IDO1 (0.43) | CYP11B1CYP11B2IDO1CYP19A1TDP1 | |
| SCHEMBL11285968 | 0.89 | CYP11B1 (0.44) | CYP11B1CYP11B2IDO1CYP19A1POLB | |
| SCHEMBL11286350 | 0.88 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1POLB | |
| SCHEMBL11273960 | 0.87 | CYP11B1 (0.52) | CYP11B1CYP11B2IDO1CYP19A1TDP1 | |
| SCHEMBL11273980 | 0.86 | CYP11B1 (0.47) | CYP11B1CYP11B2IDO1CYP19A1POLB | |
| SCHEMBL11279504 | 0.86 | IDO1 (0.45) | CYP11B1CYP11B2IDO1CYP19A1TDP1 | |
| SCHEMBL11277864 | 0.85 | CYP11B1 (0.48) | CYP11B1CYP11B2IDO1CYP19A1POLB | |
| SCHEMBL11267370 | 0.85 | CYP11B1 (0.55) | CYP11B1CYP11B2IDO1CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064244-A1 | Spermicidal 1-bis(arylalkyl)alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-11-10 | — | — | EP | disclosed |