Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270331 | 1.00 | CYP24A1 (0.63) | CYP24A1MAPTRAB9AATMHTT | |
| SCHEMBL10997822 | 0.82 | CYP24A1 (0.43) | CYP24A1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL10997826 | 0.82 | CYP24A1 (0.43) | CYP24A1MAPTRAB9AATMSMN1; SMN2 | |
| SCHEMBL11436892 | 0.80 | CYP24A1 (0.73) | CYP24A1MAPTRAB9AATMHTT | |
| SCHEMBL11145979 | 0.75 | CYP24A1 (0.58) | CYP24A1MAPTRAB9AATMHTT | |
| SCHEMBL11145976 | 0.75 | CYP24A1 (0.58) | CYP24A1MAPTRAB9AATMHTT | |
| SCHEMBL10997295 | 0.75 | MAPT (0.49) | CYP24A1MAPTHTTSMN1; SMN2PKM | |
| SCHEMBL10997297 | 0.75 | MAPT (0.49) | CYP24A1MAPTHTTSMN1; SMN2PKM | |
| SCHEMBL11147700 | 0.74 | CYP24A1 (0.62) | CYP24A1MAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL11147702 | 0.74 | CYP24A1 (0.62) | CYP24A1MAPTRAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |