Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112803 | 0.85 | GSK3B (0.47) | HDAC6HDAC1 | |
| Bromide SCHEMBL6125802 | 0.84 | GSK3B (0.46) | HPGDHDAC6HDAC1ALDH1A1 | |
| SCHEMBL6112734 | 0.83 | NPC1 (0.50) | HDAC6HDAC1 | |
| SCHEMBL16166414 | 0.83 | HDAC6 (0.52) | GAAHPGDHDAC6HTTHDAC1 | |
| SCHEMBL11272498 | 0.81 | HPGD (0.46) | GAAHPGDHDAC6HDAC1 | |
| SCHEMBL11211254 | 0.80 | NPSR1 (0.40) | GAAHPGDHDAC6HTTKDM4E | |
| SCHEMBL11213195 | 0.80 | HPGD (0.46) | GAAHPGDHDAC6HTTHDAC1 | |
| SCHEMBL11276434 | 0.78 | HDAC6 (0.54) | HPGDHDAC6HDAC1ALDH1A1 | |
| SCHEMBL11267818 | 0.77 | HPGD (0.49) | GAAHPGDHDAC6HTTKDM4E | |
| SCHEMBL11276251 | 0.77 | HPGD (0.46) | GAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |