Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | APEX1 | P27695 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646636 | 0.95 | PTGS1 (0.60) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10646639 | 0.95 | PTGS1 (0.60) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10644893 | 0.94 | PTGS1 (0.60) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10644890 | 0.94 | PTGS1 (0.60) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10642963 | 0.93 | TDP1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10642959 | 0.93 | TDP1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| Hydrochloric Acid SCHEMBL10643428 | 0.93 | TDP1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| Hydrochloric Acid SCHEMBL10643433 | 0.93 | TDP1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10645527 | 0.90 | PTGS1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10645538 | 0.90 | PTGS1 (0.61) | PTGS1ABCB11PDE4DTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057422-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |