SCHEMBL11272010

SCHEMBL11272010

CCCC[C@H]1CC[C@H](c2ccc(C(=O)OC3CCC(CCC)CC3)cc2)CC1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.60
ALDH1A1 P00352 2/20 0.57
MAPT P10636 2/20 0.57
LMNA P02545 1/20 0.57
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 2/20 0.46
NAAA Q02083 1/20 0.46
SCN1A P35498 2/20 0.39
SCN2A Q99250 2/20 0.39
SCN3A Q9NY46 2/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10591043 1.00 CYP2C9 (0.60) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11418227 1.00 CYP2C9 (0.60) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10384434 1.00 CYP2C9 (0.60) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11412244 0.97 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL14300377 0.96 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10911790 0.96 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10911787 0.96 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10911794 0.96 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL10911800 0.96 CYP2C9 (0.56) CYP2C9ALDH1A1MAPTLMNAMEN1
SCHEMBL11416210 0.96 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4331552-A Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-25 US disclosed
US-4302352-A Fluorophenylcyclohexanes, the preparation thereof and their use as components of liquid crystal dielectrics MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-11-24 US disclosed
US-4237026-A Liquid crystalline carboxylic acid esters MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-12-02 US disclosed