Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.71 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324072 | 0.94 | ACE (0.78) | ACEREN | |
| SCHEMBL682298 | 0.94 | ACE (0.78) | ACEREN | |
| SCHEMBL7318593 | 0.93 | ACE (0.77) | ACE | |
| SCHEMBL7330167 | 0.93 | ACE (0.77) | ACE | |
| SCHEMBL7327307 | 0.88 | ACE (0.70) | ACEREN | |
| SCHEMBL11268803 | 0.87 | ACE (0.66) | ACE | |
| SCHEMBL30999001 | 0.86 | ACE (0.71) | ACE | |
| Lisinopril Anhydrous SCHEMBL18938417 | 0.85 | ACE (0.98) | ACE | |
| Lisinopril Anhydrous SCHEMBL21373192 | 0.85 | ACE (0.98) | ACE | |
| SCHEMBL7325587 | 0.84 | ACE (0.65) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049506-A1 | N-carboxyalkyl dipeptides, a process for preparing and a pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-04-14 | — | — | EP | disclosed |