Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.76 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273021 | 0.89 | ADRB3 (0.77) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL8406644 | 0.88 | ADRB3 (0.69) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL10775119 | 0.88 | SLC2A1 (0.97) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL11269959 | 0.87 | ADRB3 (0.57) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL11166762 | 0.86 | ADRB3 (0.67) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL9671238 | 0.86 | ADRB3 (0.78) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL7150308 | 0.86 | ADRB3 (0.78) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL11183468 | 0.86 | ADRB3 (0.78) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL7150315 | 0.86 | ADRB3 (0.78) | SLC2A1ADRB3ADRB2ADRB1GLA | |
| SCHEMBL4611391 | 0.85 | ADRB3 (1.00) | SLC2A1ADRB3ADRB2ADRB1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063004-A1 | Secondary amines, processes for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1982-10-20 | — | — | EP | claimed |
| EP-0063004-A1 | Secondary amines, processes for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1982-10-20 | — | — | EP | disclosed |