Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24554063 | 0.91 | ESR2 (0.45) | ESR2SPHK1ACHESPHK2TP53 | |
| SCHEMBL11277384 | 0.88 | ESR2 (0.42) | ESR2HRH3SPHK1FFAR1SPHK2 | |
| SCHEMBL11282998 | 0.87 | SPHK1 (0.35) | ESR2SPHK1FFAR1NPC1RAB9A | |
| SCHEMBL11280913 | 0.84 | CYP2C9 (0.48) | ESR2SPHK1SPHK2 | |
| SCHEMBL11280022 | 0.82 | SPHK1 (0.41) | ESR2SPHK1SPHK2 | |
| SCHEMBL20976648 | 0.82 | ESR2 (0.40) | ESR2HRH3FFAR1NPC1RAB9A | |
| SCHEMBL11190830 | 0.82 | ESR2 (0.45) | ESR2HRH3FFAR1NPC1RAB9A | |
| SCHEMBL11190814 | 0.82 | ESR2 (0.45) | ESR2HRH3FFAR1NPC1RAB9A | |
| SCHEMBL11286899 | 0.81 | SPHK1 (0.43) | SPHK1SPHK2 | |
| SCHEMBL20083082 | 0.81 | BCL2L1 (0.42) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022183-B1 | DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS | MERCK PATENT GmbH (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4330426-A | Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0022183-A2 | Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements | MERCK PATENT GmbH (DE) | 1981-01-14 | — | — | EP | disclosed |