Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275399 | 1.00 | TDP1 (0.55) | TDP1TSHRSMN1; SMN2ERN1HSD17B10 | |
| SCHEMBL27642032 | 0.87 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2ERN1HSD17B10 | |
| SCHEMBL27641952 | 0.87 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2ERN1HSD17B10 | |
| SCHEMBL10975917 | 0.85 | TDP1 (0.69) | TDP1TSHRSMN1; SMN2ERN1HSD17B10 | |
| SCHEMBL10975921 | 0.85 | TDP1 (0.69) | TDP1TSHRSMN1; SMN2ERN1HSD17B10 | |
| SCHEMBL27780521 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL1343573 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL1343574 | 0.83 | MAPT (0.56) | SMN1; SMN2MAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL6786004 | 0.81 | ERN1 (0.61) | SMN1; SMN2ERN1MAPTALDH1A1KMT2A | |
| SCHEMBL6786002 | 0.81 | ERN1 (0.61) | SMN1; SMN2ERN1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |