SCHEMBL11275601

SCHEMBL11275601

Fc1ccc(C(Cl)Cn2cncn2)cc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.59
KMT2A Q03164 1/20 0.46
LMNA P02545 1/20 0.40
HSP90AA1 P07900 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
CYP2C19 P33261 1/20 0.40
ADRA1A P35348 1/20 0.40
CYP51A1 Q16850 1/20 0.40
ABL1 P00519 5/20 0.40
SRC P12931 3/20 0.40
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11375336 0.85 CYP19A1 (0.51) CYP19A1KMT2ALMNACYP3A4ALDH1A1
SCHEMBL11127036 0.83 CYP19A1 (0.56) CYP19A1KMT2ALMNAHSP90AA1SRC
Hydrochloric Acid SCHEMBL11228319 0.82 CYP19A1 (0.54) CYP19A1KMT2ALMNAHSP90AA1SRC
SCHEMBL11610591 0.81 CYP19A1 (0.47) CYP19A1KMT2ALMNACYP3A4ALDH1A1
SCHEMBL11273790 0.81 CYP19A1 (0.59) CYP19A1KMT2ALMNAHSP90AA1CYP3A4
SCHEMBL9695247 0.81 CYP19A1 (0.59) CYP19A1KMT2ALMNAHSP90AA1CYP3A4
SCHEMBL27602502 0.78 CYP19A1 (0.56) CYP19A1KMT2ALMNAHSP90AA1CYP3A4
SCHEMBL54018 0.77 CYP19A1 (0.59) CYP19A1KMT2ALMNAHSP90AA1CYP3A4
SCHEMBL27602500 0.77 CYP19A1 (0.55) CYP19A1KMT2ALMNAHSP90AA1CYP3A4
SCHEMBL3319920 0.74 CYP19A1 (0.67) CYP19A1KMT2ALMNAHSP90AA1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007589-B1 INSECTICIDE AGENTS COMPRISING CARBAMATE AS ACTIVE INGREDIENT AND TRIAZOLE DERIVATIVES AS SYNERGISTS BASF Aktiengesellschaft (DE) 1981-05-13 EP claimed
US-4256754-A PHENYL-1,2,4-TRIAZOLE DERIVATIVE, CARBAMATE BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US claimed
EP-0007589-A1 Insecticide agents comprising carbamate as active ingredient and triazole derivatives as synergists BASF Aktiengesellschaft (DE) 1980-02-06 EP claimed
US-4344961-A MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
US-4298615-A INSECTICIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 1981-11-03 US disclosed
US-4256754-A PHENYL-1,2,4-TRIAZOLE DERIVATIVE, CARBAMATE BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
EP-0023637-A1 Substituted 2,3-dihydrobenzofurylmethyl-cyclopropanecarboxylic acid esters, process for their preparation, process for combatting parasites, and agents therefor BASF Aktiengesellschaft (DE) 1981-02-11 EP disclosed
EP-0012273-A1 Carboxylic acid esters, process for their preparation and their use as pesticides BASF Aktiengesellschaft (DE) 1980-06-25 EP disclosed
EP-0007589-A1 Insecticide agents comprising carbamate as active ingredient and triazole derivatives as synergists BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed