Chloromethane

Chloromethane

SCHEMBL1127607

C=CC(=O)OCCN(CC)CC.CCl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.53
HPGD P15428 2/20 0.53
THRB P10828 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TP53 P04637 2/20 0.48
HIF1A Q16665 2/20 0.48
CYP3A4 P08684 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 2/20 0.44
POLB P06746 2/20 0.44
KMT2A Q03164 2/20 0.44
CHRM2 P08172 3/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2D6 P10635 2/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14924 0.96 TSHR (0.57) TSHRHPGDTHRBALDH1A1TP53
Ethyl Chloride SCHEMBL28779028 0.95 TSHR (0.52) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL27554838 0.94 TSHR (0.55) TSHRHPGDTHRBALDH1A1TP53
Ammonia Solution, Strong SCHEMBL27767919 0.94 TSHR (0.55) TSHRHPGDTHRBALDH1A1TP53
Hydrochloric Acid SCHEMBL9185674 0.94 TSHR (0.55) TSHRHPGDTHRBALDH1A1TP53
Hydrochloric Acid SCHEMBL28153939 0.93 TSHR (0.53) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL10698787 0.92 TSHR (0.57) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL11118611 0.91 TSHR (0.49) TSHRHPGDTHRBALDH1A1TP53
Acetic Acid SCHEMBL9226545 0.91 TSHR (0.52) TSHRHPGDTHRBALDH1A1TP53
Acrylic Acid Ethyl Ester SCHEMBL10940378 0.91 TSHR (0.52) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023154840-A1 HIGH MOLECULAR WEIGHT GPAM WITH ANIONIC POLYSACCHARIDE PROMOTER KEMIRA OYJ (FI) 2023-08-17 WO claimed
WO-2023154839-A1 HIGH MOLECULAR WEIGHT GPAM WITH ANIONIC POLYMERIC PROMOTER KEMIRA OYJ (FI) 2023-08-17 WO claimed
EP-2109441-B1 POLYSILOXANE BLOCK COPOLYMERS BASF SE (DE) 2016-01-27 EP claimed
US-8378038-B2 Polysiloxane block copolymers BASF SE (DE) 2013-02-19 US claimed
US-8147814-B2 Personal care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-8148318-B2 Home or fabric care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US claimed
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KOROSKENYI BALINT 2010-12-02 US claimed
US-7732525-B2 Polymers for paper and paperboard coatings CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2010-06-08 US claimed
EP-2109441-A2 POLYSILOXANE BLOCK COPOLYMERS Ciba Holding Inc. (CH) 2009-10-21 EP claimed
EP-2046932-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES Ciba Holding Inc. (CH) 2009-04-15 EP claimed
US-20080199418-A1 Polysiloxane block copolymers BASF SE (DE) 2008-08-21 US claimed
WO-2008095822-A2 POLYSILOXANE BLOCK COPOLYMERS CIBA HOLDING INC. (CH) 2008-08-14 WO claimed
US-20080033106-A1 Composition for improving wettability of surfaces CIBA SPECIALTY CHEMICALS CORP. 2008-02-07 US claimed
WO-2008015138-A2 COMPOSITION FOR IMPROVING WETTABILITY OF SURFACES CIBA HOLDING INC. (CH) 2008-02-07 WO claimed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO claimed
CN-114206955-B Method for controlling the production of excess water and aqueous fluids in oil and gas wells 能源解决方案(美国)有限责任公司 2024-01-30 CN disclosed
CN-116829675-A Inversion surfactant for inverse emulsion 能源解决方案(美国)有限责任公司 2023-09-29 CN disclosed
US-6369182-B1 MONOMERS INCLUDE (METH)ACRYLAMIDE AND QUATERNARY SALT; CLARIFICATION OF SLUDGE; SEWAGE TREATMENT NALCO CHEMICAL COMPANY 2002-04-09 US disclosed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO disclosed
WO-2001027173-A1 CATIONIC LATEX TERPOLYMERS FOR WASTEWATER TREATMENT NALCO CHEMICAL COMPANY (US) 2001-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303750-A1 POLYSILOXANE BLOCK COPOLYMERS KRT18, PUF60, SCNN1B TSHR 4325/4885HPGD 4143/4885THRB 1165/4885
US-20080199418-A1 Polysiloxane block copolymers KRT18, PUF60, SCNN1B TSHR 4325/4885HPGD 4143/4885THRB 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.