Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034846 | 0.89 | TSHR (0.48) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL5973483 | 0.89 | ATM (0.50) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL5973493 | 0.89 | ATM (0.50) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL5973993 | 0.89 | ATM (0.50) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7636692 | 0.85 | TSHR (0.52) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7638858 | 0.85 | TSHR (0.52) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL11243556 | 0.85 | ATM (0.54) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL20913247 | 0.83 | ATM (0.60) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7637532 | 0.83 | HCAR2 (0.56) | ATMTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7637527 | 0.83 | HCAR2 (0.56) | ATMTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022978-B1 | ACETYLACETOXYALKYL ALLYL ETHERS, THEIR PREPARATION AND UTILIZATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0022978-A1 | Acetylacetoxyalkyl allyl ethers, their preparation and utilization | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |