Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.82 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.55 |
| ▸ | PTAFR | P25105 | 3/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CASP7 | P55210 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002651 | 0.90 | ALPG (1.00) | ALPGTBXAS1PTAFRAKR1B1MET | |
| SCHEMBL11263411 | 0.89 | ALPG (0.98) | ALPGTBXAS1PTAFRAKR1B1MET | |
| SCHEMBL11263399 | 0.89 | ALPG (0.98) | ALPGTBXAS1PTAFRAKR1B1MET | |
| SCHEMBL11279129 | 0.89 | ALPG (0.84) | ALPGTBXAS1PTAFRAKR1B1KDM4E | |
| Hydrochloric Acid SCHEMBL11272525 | 0.89 | ALPG (0.98) | ALPGTBXAS1PTAFRAKR1B1MET | |
| SCHEMBL11005652 | 0.88 | ALPG (0.82) | ALPGTBXAS1PTAFRAKR1B1KDM4E | |
| SCHEMBL11263888 | 0.88 | ALPG (0.82) | ALPGTBXAS1PTAFRAKR1B1KDM4E | |
| Hydrochloric Acid SCHEMBL11263169 | 0.87 | ALPG (0.80) | ALPGTBXAS1PTAFRAKR1B1KDM4E | |
| SCHEMBL11263403 | 0.87 | ALPG (0.80) | ALPGTBXAS1PTAFRAKR1B1MET | |
| SCHEMBL11279191 | 0.86 | ALPG (0.79) | ALPGTBXAS1PTAFRAKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348396-A | Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |