SCHEMBL1127634

SCHEMBL1127634

S=c1c2ccccc2oc2cccc([S+](c3ccccc3)c3ccc(Sc4ccccc4)cc3)c12

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5125869 0.69 NPC1 (0.39) NPC1ALDH1A1LMNAMAPTHPGD
SCHEMBL3522339 0.68 MEN1 (0.31) ALDH1A1MAPTMAOA
SCHEMBL31591283 0.68 HPGD (0.48) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL92105 0.68 HPGD (0.48) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL3525780 0.68 NPC1 (0.38) NPC1ALDH1A1LMNAMAPTHPGD
Bromide SCHEMBL3519084 0.68 NPC1 (0.38) NPC1ALDH1A1LMNAMAPTHPGD
Bromide SCHEMBL4678003 0.66 HPGD (0.47) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL7612105 0.66 HPGD (0.47) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Iodide SCHEMBL7997284 0.66 HPGD (0.47) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL92199 0.66 HPGD (0.45) ALDH1A1LMNAMAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed