Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287414 | 0.96 | TBXA2R (0.37) | TBXA2RLMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL11283327 | 0.92 | TBXA2R (0.38) | TBXA2RLMNAHIF1AKMT2ACASP1 | |
| SCHEMBL11290651 | 0.89 | MAPT (0.38) | TBXA2RLMNAALDH1A1ADRB2KMT2A | |
| SCHEMBL11290106 | 0.86 | TBXA2R (0.40) | TBXA2RKMT2A | |
| SCHEMBL11277087 | 0.86 | PMP22 (0.45) | LMNAALDH1A1CYP3A4HIF1AADRB2 | |
| SCHEMBL11282282 | 0.86 | PMP22 (0.39) | TBXA2RLMNAHIF1AADRB2KMT2A | |
| SCHEMBL11285937 | 0.86 | PMP22 (0.35) | TBXA2RLMNAALDH1A1HIF1AKMT2A | |
| SCHEMBL11279310 | 0.83 | KMT2A (0.44) | LMNAALDH1A1CYP3A4CCR5KMT2A | |
| SCHEMBL11286090 | 0.83 | KMT2A (0.44) | LMNAALDH1A1CYP3A4CCR5KMT2A | |
| SCHEMBL11277075 | 0.82 | TBXA2R (0.37) | TBXA2RLMNAALDH1A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | claimed |
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |