SCHEMBL11278060

SCHEMBL11278060

COCC(=O)SCC(=O)N(c1c(C)ccc(C)c1C)C(C)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
PLA2G1B P04054 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ATG4B Q9Y4P1 1/20 0.40
HPGD P15428 3/20 0.32
RAB9A P51151 1/20 0.32
RORC P51449 1/20 0.31
TSHR P16473 1/20 0.31
RECQL P46063 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278063 1.00 MEN1 (0.40) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11282913 0.91 MEN1 (0.38) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11282916 0.91 MEN1 (0.38) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11282726 0.91 KMT2A (0.38) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11282724 0.91 KMT2A (0.38) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11273887 0.89 MEN1 (0.41) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11273889 0.89 MEN1 (0.41) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11276786 0.88 MEN1 (0.40) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11276784 0.88 MEN1 (0.40) MEN1PLA2G1BHTTKMT2ANPSR1
SCHEMBL11282415 0.87 MEN1 (0.40) MEN1PLA2G1BHTTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313957-A Pesticidal sulfur containing amides derived from aniline and the method of preparation thereof RHONE-POULENC AGROCHIMIE (FR) 1982-02-02 US disclosed