Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258960 | 0.72 | DPP4 (0.36) | DPP4 | |
| SCHEMBL21363994 | 0.72 | DPP4 (0.36) | DPP4 | |
| SCHEMBL22044790 | 0.72 | DPP4 (0.36) | DPP4 | |
| SCHEMBL5260452 | 0.72 | DPP4 (0.36) | DPP4 | |
| SCHEMBL18200185 | 0.70 | DPP4 (0.35) | DPP4 | |
| SCHEMBL9713932 | 0.70 | DPP4 (0.32) | DPP4 | |
| SCHEMBL1273728 | 0.70 | DPP4 (0.35) | DPP4 | |
| SCHEMBL4925574 | 0.70 | DPP4 (0.32) | DPP4 | |
| SCHEMBL18948680 | 0.68 | OPRL1 (0.34) | DPP4 | |
| SCHEMBL27523829 | 0.68 | OPRL1 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283022-A1 | FURO Ý3, 2-B¨PYRR0L-3-0NES AS CATHEPSIN S INHIBITORS | Amura Therapeutics Limited (GB) | 2011-02-16 | — | — | EP | disclosed |