Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.53 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274252 | 0.93 | POLB (0.60) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11286578 | 0.92 | NR1I2 (0.60) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11274742 | 0.86 | POLB (0.58) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11270019 | 0.86 | POLB (0.58) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11271387 | 0.86 | NR1I2 (0.74) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11280701 | 0.86 | CTDSP1 (0.59) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9684902 | 0.85 | NR1I2 (0.76) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11275654 | 0.83 | NR1I2 (0.60) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11273867 | 0.83 | NR1I2 (0.57) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11286574 | 0.82 | MAPT (0.70) | NR1I2PGRSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358448-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-11-09 | — | — | US | claimed |
| US-4358448-A | ANTIBIOTICS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-11-09 | — | — | US | disclosed |