Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CDC42 | P60953 | 1/20 | 0.62 |
| ▸ | RAC1 | P63000 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934093 | 0.89 | POLB (0.73) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11286536 | 0.88 | POLB (0.72) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL15932269 | 0.87 | POLB (0.70) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL13825986 | 0.86 | POLB (0.77) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11443395 | 0.86 | POLB (0.69) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL16002868 | 0.84 | POLB (0.77) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11730090 | 0.84 | POLB (0.72) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11737850 | 0.80 | POLB (0.65) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11454281 | 0.80 | TDP1 (0.61) | POLBPTGS2AKR1C3AKR1C2PTGS1 | |
| SCHEMBL11732002 | 0.80 | POLB (0.60) | POLBPTGS2AKR1C3AKR1C2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |