SCHEMBL11278376

SCHEMBL11278376

CCC(=O)SCC(=O)N(c1c(C)ccc(Br)c1C)C(C)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
MEN1 O00255 1/20 0.38
PLA2G1B P04054 1/20 0.38
HTT P42858 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
RORC P51449 1/20 0.34
ALDH1A1 P00352 2/20 0.31
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11278378 1.00 KMT2A (0.38) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11282642 0.92 KMT2A (0.37) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11282645 0.92 KMT2A (0.37) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11273887 0.91 MEN1 (0.41) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11273889 0.91 MEN1 (0.41) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11267461 0.91 HTT (0.36) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11267457 0.91 HTT (0.36) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11268656 0.90 KMT2A (0.38) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11282726 0.90 KMT2A (0.38) KMT2ANPSR1MEN1PLA2G1BHTT
SCHEMBL11282724 0.90 KMT2A (0.38) KMT2ANPSR1MEN1PLA2G1BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313957-A Pesticidal sulfur containing amides derived from aniline and the method of preparation thereof RHONE-POULENC AGROCHIMIE (FR) 1982-02-02 US disclosed