Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | APAF1 | O14727 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278429 | 1.00 | TDP1 (0.51) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10531390 | 0.91 | TDP1 (0.53) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10531398 | 0.91 | TDP1 (0.53) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9481299 | 0.91 | TDP1 (0.63) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9481301 | 0.91 | TDP1 (0.63) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10345545 | 0.90 | TDP1 (0.49) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10528977 | 0.90 | TDP1 (0.49) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10345544 | 0.90 | TDP1 (0.49) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10528972 | 0.90 | TDP1 (0.49) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL8869412 | 0.90 | KMT2A (0.50) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048915-A2 | New cephem compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |